Found 51 matching trials
Study to Evaluate the Safety and Efficacy of Phenoptin⢠in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels
PHASE3The primary objective of this study is to evaluate the efficacy of Phenopti...
Location
Multiple Locations
Phase 3 Open-label Study to Evaluate the Response and Safety of KuvanĀ® in Subjects With Phenylketonuria
PHASE3This is an open-label, non-comparative, Phase 3 study to evaluate the degre...
Location
Please contact Merck KGaA Communication Center
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
PHASE2The investigators will investigate the effect of blood phenylalanine on Kuv...
Location
Department of Biochemistry & Molecular Biology
Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKU
PHASE3This multicenter, open label study is designed to evaluate the safety of Ku...
Location
Multiple Locations
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
NAMore patients with chronic obstructive pulmonary disease (COPD) die from ca...
Location
Augusta University
Evaluation of BH4 Responsiveness in Our PKU Patients
PHASE1This study aims to evaluate BH4 responsiveness in our PKU patients and to c...
Status
Active Not Recruiting
Location
Sohag Faculty of Medicine
Study of Indoleamine 2,3-dioxygenase Activity, Serum Levels of Cytokines, BDNF, BH4 and Mirtazapine Efficacy in Fibromyalgia Syndrome
PHASE2This study aims to investigate the anti-nociceptive biogenic amine (seroton...
Location
Siriraj Hospital, Mahidol University
The Effectiveness of Kuvan in Amish PKU Patients
PHASE4The purpose of this study is to determine if Amish patients with PKU show r...
Location
University Hospitals Cleveland Medical Center
Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies
NAStudy background
High blood pressure during pregnancy is a worldwide healt...
Location
Oxford University Hospitals NHS Foundation Trust
A Study of PTC923 (CNSA-001) in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia
PHASE1This study has been designed to demonstrate the safety, pharmacokinetics (P...
Location
University of Minnesota